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UNC5CL Rabbit anti-Human, Non-human primate, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523295

Catalog No. PIPA523295


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Description

Description

UNC5CL is a membrane protein belonging to theUNC-5 family with a death domain and a ZU5 domain and is known to interact with p65/RELA and NFKB1. UNC5CL is known to interact with subunit p105 of NF-kappaB  and transactivator p65 and is thus involved in inhibition of NF-kappaB activation and NF-kappaB-dependent transcription by inhibiting the binding of NF-kappaB to its target sequence (providing an alternative regulatory mechanism for NF-kappaB-mediated transcription). This regulatory protein sensitizes cells to apopotosis induced by TNF and TRAIL.
Specifications

Specifications

UNC5CL
Polyclonal
Unconjugated
UNC5CL
Liquid
UNC5CL
Synthetic peptide (GPERGGARDNQGLELDEK (aa500-517)∽^QEEPVSQPTPQLENEVSR (aa49-66)) of UNC5CL protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Non-human Primate
Immunohistochemistry (Paraffin)
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q8IV45
MUXA, ZUD, UNC5C-like protein, ZU5 and death domain containing, protein unc-5 homolog C-like
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
222643
Documents
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