UNC5CL Rabbit anti-Human, Non-human primate, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523295
DescriptionUNC5CL is a membrane protein belonging to theUNC-5 family with a death domain and a ZU5 domain and is known to interact with p65/RELA and NFKB1. UNC5CL is known to interact with subunit p105 of NF-kappaB and transactivator p65 and is thus involved in inhibition of NF-kappaB activation and NF-kappaB-dependent transcription by inhibiting the binding of NF-kappaB to its target sequence (providing an alternative regulatory mechanism for NF-kappaB-mediated transcription). This regulatory protein sensitizes cells to apopotosis induced by TNF and TRAIL.
|Synthetic peptide (GPERGGARDNQGLELDEK (aa500-517)∽^QEEPVSQPTPQLENEVSR (aa49-66)) of UNC5CL protein.|
|Antigen affinity chromatography|
|Human, Non-human Primate|
|PBS with 0.05% BSA and 0.05% sodium azide|
|MUXA, ZUD, UNC5C-like protein, ZU5 and death domain containing, protein unc-5 homolog C-like|
|-20° C, Avoid Freeze/Thaw Cycles|
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