VEGF Receptor 2 Goat anti-Human, Mouse, Polyclonal, Invitrogen
Goat Polyclonal Antibody
Manufacturer: Invitrogen PA120207
PA1-20207 detects VEGF Receptor 2 in mouse samples. PA1-20207 has been successfully used in ELISA, neutralization, immunohistochemistry and Western blot procedures. Neutralization: Anti-Mouse VEGF Receptor 2 has the ability to neutralize the biological activity of recombit mouse VEGF Receptor 2 on HUVE (human umbilical vein endothelial) cells in the presence of recombit mouse VEGF Receptor 2/Fc (50 ng/mL) and recombit mouse VEGF (5 ng/mL). The PA1-20207 immunogen is recombit extracellular domain of mouse VEGF receptor 2, expressed in mouse NSO cells. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Vascular endothelial growth factors (VEGFs) are a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGF Receptor 1 and VEGF Receptor 2 are both expressed in an endothelial cell-specific manner. They are detectable in virtually all tissues in adults and embryos. Monocytes express VEGF Receptor 1 and VEGF Receptor 2. VEGF Receptor 2 is involved in commitment of endothelial-cell lineages and to cell proliferation, while VEGF Receptor 1 seems to be responsible for guiding endothelial cells into the proper spatial organization of the lumen-containing vessels. VEGF Receptor 2 binds VEGF with high affinity but does not bind PIGF.
|VEGF Receptor 2|
|Recombit extracellular domain of mouse VEGF receptor 2, expressed in mouse NSO cells.|
|Antigen affinity chromatography|
|Immunohistochemistry, Neutralization, Western Blot|
|PBS with no preservative; pH 7.4|
|6130401C07, Flk-1, Flk1, Krd-1, Ly73, VEGFR-2, VEGFR2, sVEGFR-2, CD309, KDR|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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