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VEGF Receptor 2 Goat anti-Human, Mouse, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA120207

Catalog No. PA120207


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Description

Description

PA1-20207 detects VEGF Receptor 2 in mouse samples. PA1-20207 has been successfully used in ELISA, neutralization, immunohistochemistry and Western blot procedures. Neutralization: Anti-Mouse VEGF Receptor 2 has the ability to neutralize the biological activity of recombit mouse VEGF Receptor 2 on HUVE (human umbilical vein endothelial) cells in the presence of recombit mouse VEGF Receptor 2/Fc (50 ng/mL) and recombit mouse VEGF (5 ng/mL). The PA1-20207 immunogen is recombit extracellular domain of mouse VEGF receptor 2, expressed in mouse NSO cells. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Vascular endothelial growth factors (VEGFs) are a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGF Receptor 1 and VEGF Receptor 2 are both expressed in an endothelial cell-specific manner. They are detectable in virtually all tissues in adults and embryos. Monocytes express VEGF Receptor 1 and VEGF Receptor 2. VEGF Receptor 2 is involved in commitment of endothelial-cell lineages and to cell proliferation, while VEGF Receptor 1 seems to be responsible for guiding endothelial cells into the proper spatial organization of the lumen-containing vessels. VEGF Receptor 2 binds VEGF with high affinity but does not bind PIGF.
Specifications

Specifications

VEGF Receptor 2
Polyclonal
Unconjugated
KDR
Liquid
KDR
Recombit extracellular domain of mouse VEGF receptor 2, expressed in mouse NSO cells.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry, Neutralization, Western Blot
0.1 mg/mL
PBS with no preservative; pH 7.4
P35968, P35918
6130401C07, Flk-1, Flk1, Krd-1, Ly73, VEGFR-2, VEGFR2, sVEGFR-2, CD309, KDR
Goat
IgG
25 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
16542, 3791
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