VEGF Receptor 3 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA137711

Catalog No. 01-673-466

Description

Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is placenta or breast carcinoma.

Three cell membrane receptor tyrosine kinases, Flt (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4 (also designated VEGF-R3), putatively involved in the frowth of endothelial cells, are characterized by the presence of seven immuno-globulin-like sequences in their extracellular domain. On the basis of structural similarity to Flt and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either CEGF or VEGF-related ligand.

Specifications

• Antigen: VEGF Receptor 3
• Classification: Polyclonal
• Formulation: TBS with 1% BSA and <0.1% sodium azide; pH 7.6
• Gene Accession No.: P35916
• Gene Alias: FLT41, PCL, VEGFR3
• Host Species: Rabbit
• Isotype: IgG
• Quantity: 7 mL
• Storage Requirements: 4° C
• Primary or Secondary: Primary
• Gene ID (Entrez): 2324

• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Gene: FLT4
• Format: Liquid
• Gene Symbols: FLT4
• Immunogen: Synthetic peptide derived from C-terminus of human Flt-4 protein
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human