Thermo Scientific™ Lab Vision™ Vitamin D Receptor (VDR) Ab-1, Rat Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ Vitamin D Receptor (VDR) Ab-1, Rat Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ RT200PABX

Catalog No. RT200PABX

Description

Provide accurate, reproducible results with the Thermo Scientific™ Vitamin D Receptor (VDR) Ab-1, Rat Monoclonal Antibody.

VDR is a member of super family of steroid hormone receptors. It is known to play role in cellular growth and differentiation, calcium and phosphorus metabolism and bone remodeling. Human breast carcinomas, leukemias, and prostatic carcinoma cells express VDR, which can modify their growth and differentiation. In avians, VDR appears as a doublet of 58kDa and 60kDa.

Host Species: Rat

Clone: 9A7γ.E10.E4

Isotype: IgG2b

Species Reactivity: Human, Pig, Mouse, Rat, Hamster, Frog, Chicken and Fish. Others not known.

Epitope: aa 89-105 (near the DNA-binding domain)

Immunogen: Vitamin D receptor protein from chicken intestine

Molecular Weight: 53kDa

Positive Control: LNCAP cells, HeLa cells

Cellular Localization: Nuclear Ab-1 reacts with both the occupied and unoccupied forms of VDR and shows no cross reaction with estrogen and glucocorticoid receptors. It is excellent for biochemical and histochemical applications.

Recommended for:

• Western Blotting
• Gel Supershift Assay

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Vitamin D Receptor (VDR) Ab-1
• Classification: Monoclonal
• Concentration: 1mg/mL
• Format: Concentrated
• Immunogen: Vitamin D receptor protein from chicken intestine
• Quantity: 200μL
• Research Discipline: Nuclear Receptors
• Primary or Secondary: Primary
• Target Species: Chicken, Fish, Frog, Hamster, Human, Murine, Porcine

• Applications: Western Blot
• Clone: 9A7gamma.E10.E4
• Conjugate: Unconjugated
• Host Species: Rat
• Isotype: IgG2b
• Regulatory Status: RUO
• Type: Primary
• Monoclonal or Polyclonal: Monoclonal