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WDR4, Polyclonal, Invitrogen™
Description
Required for 7-methylguanosine modification of tRNA. This protein is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD). which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes. including cell cycle progression. signal transduction. apoptosis. and gene regulation. This protein is excluded as a candidate for a form of nonsyndromic deafness (DFNB10). but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternative splicing of this gene generates at least 3 transcript variants. two of which diverge at the 3' UTR and thus encode the same protein products.
Specifications
Specifications
| Antigen | WDR4 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 1mg/mL |
| Conjugate | Unconjugated |
| Gene | WDR4 |
| Gene Accession No. | P57081 |
| Gene Alias | TRM82 |
| Gene Symbols | WDR4 |
| Host Species | Chicken |
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