West Nile Virus Envelope Mouse anti-Virus, Clone: F50F, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA518281
This antibody is specific for the envelope protein of West Nile Virus. It detects West Nile Virus, St. Louis Encephalitis, Japanese Encephalitis and Dengue, and does not react with Yellow Fever, Tick-Borne Encephalitis, Eastern Equine Encephalitis, Western Equine Encephalitis, Powassan, La Crosse Encephalitis or Venezuelan Equine Encephalitis. Purity is >90%.West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins which play a major role for WNV entry into target cells. The viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway as delivery of core gene delivery into the striatum of mouse brain and skeletal muscle resulted in cell death and inflammation.
|West Nile Virus Envelope|
|PBS with 0.1% sodium azide; pH 7.2|
|WNV envelope; West Nile envelope|
|West Nile Virus native protein|
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