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WIBG Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA524202

Catalog No. PIPA524202

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as a EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions. May bind RNA.
Specifications

Specifications

WIBG
Polyclonal
PBS with 0.09% sodium azide
Q9BRP8, Q8CHP5
PYM, partner of Y14 and mago, protein wibg homolog
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
78428, 84305
Immunohistochemistry, Western Blot
Unconjugated
PYM1
Liquid
PYM1
KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human WIBG
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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