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WNT10A Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520542

Catalog No. PIPA520542


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Description

Description

A suggested positive control is RAW264.7 cell lysate. PA5-20542 can be used with blocking peptide PEP-0662.

Wnt10a is a member of the Wnt family, a gene family that encodes secreted signaling proteins that play crucial roles in normal development such as regulation of cell fate and patterning during embryogenesis as well as neoplastic transformation. Elevated levels of Wnt10a have been detected in several human tumors and cancer cell lines including colorectal cancer and chronic lymphocytic leukemia and it has been suggested that uncontrolled Wnt signaling may contribute to the defect in apoptosis that characterizes these maligcies. Recently, a mutation in Wnt10a was found to be associated with odonto-onycho-dermal dysplasia, an autosomal recessive ectodermal dysplasia.
Specifications

Specifications

Wnt10a
Polyclonal
Unconjugated
WNT10A
Liquid
WNT10A
A 14 amino acid peptide from near the carboxy terminus of human Wnt10a.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9GZT5, P70701
OODD, SSPS, STHAG4; protein Wnt-10a
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
22409, 316527, 80326
Documents
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