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WNT4 Goat anti-Human, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA19118

Catalog No. 01-674-398


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Description

Description

This antibody is predicted to react with mouse and rat based on sequence homology.

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome.
Specifications

Specifications

Wnt4
Polyclonal
Unconjugated
WNT4
Liquid
WNT4
Internal sequence corresponding to amino acids C-SNWLYLAKLSSVGS.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunofluorescence, peptide-ELISA, Western Blot
0.5 mg/mL
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
P56705
WNT4; wingless-type MMTV integration site family, member 4; WNT-4; WNT-4 protein precursor
Goat
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
54361
Documents
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