WNT5A Mouse anti-Human, Clone: 3D10, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA515511

Catalog No. PIMA515511

Description

MA5-15511 targets WNT5A in IHC and WB applications and shows reactivity with Human samples. The MA5-15511 immunogen is purified recombit fragment of WNT5A expressed in E. Coli.<br>. MA5-15511 detects WNT5A which has a predicted molecular weight of approximately 42.3kDa.

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98%, 98% and 87% amino acid identity to the mouse, rat and the xenopus Wnt5A protein, respectively. The experiments performed in Xenopus laevis embryos identified that human frizzled-5 is the receptor for the Wnt5A ligand and the Wnt5A/hFz5 signaling mediates axis induction.

Specifications

• Antigen: WNT5A
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: WNT5A
• Gene Alias: hWNT5A; WNT5A
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Clone: 3D10
• Formulation: ascites with 0.03% sodium azide
• Gene Accession No.: P41221
• Gene Symbols: WNT5A
• Immunogen: Purified recombit fragment of WNT5A expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 7474
• Product Type: Antibody
• Isotype: IgG1