WNT5A Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527230
PA5-27230 targets WNT5A in WB applications and shows reactivity with Human samples. The PA5-27230 immunogen is recombit fragment corresponding to a region within amino acids 41 and 380 of Human WNT5A. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98%, 98% and 87% amino acid identity to the mouse, rat and the xenopus Wnt5A protein, respectively. The experiments performed in Xenopus laevis embryos identified that human frizzled-5 (hFz5) is the receptor for the Wnt5A ligand and the Wnt5A/hFz5 signaling mediates axis induction.
|Recombit fragment corresponding to a region within amino acids 41 and 380 of Human WNT5A|
|Antigen affinity chromatography|
|PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7|
|hWNT5A, WNT-5A protein, protein Wnt-5a|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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