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WWOX Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA14400

Catalog No. PA14400


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Description

Description

PA1-4400 detects the WW domain-containing oxidoreductase (WWOX) in human and mouse samples. PA1-4400 has been successfully used in Western blot procedures. PA1-4400 immunizing peptide corresponds to the peptide representing residues 89-107 of WWOX. This sequence is 100% conserved in human, mouse, chimpanzee, and orangutan.

WW domain-containing oxidoreductase WWOX, also known as WOX1 or FOR, is a proapoptotic protein and a tumor suppressor gene. Because mutation or deletion in the coding region of WWOX is rarely found, it is speculated that the appearance of aberrant transcripts affects progression of many cancers. In addition, protein levels of WWOX, its Tyr33-phosphorylated form, and WOX2 are significantly down-regulated in the neurons of Alzheimer ft.s hippocampi.  
Specifications

Specifications

WWOX
Polyclonal
Unconjugated
WWOX
Liquid
WWOX
Synthetic peptide: R(89) L A F T V D D N P T K P T T R Q R Y(107)
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9NZC7, Q91WL8
WW domain-containing oxidoreductase, WOX1, FOR, Fragile site FRA16D oxidoreductase
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
51741, 80707
Documents
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