XIAP Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA522812
DescriptionThe human X chromosome linked Inhibitor of Apoptosis Protein (XIAP) is a major member of the inhibitor of apoptosis (IAP) family. XIAP functions by direct binding and inhibition of several caspases, including Caspase 3, Caspase 7 and Caspase 9. During apoptosis XIAP is specifically cleaved by Caspase 3 and partially loses its function. In addition to blocking the apoptosis signaling pathway, XIAP can also bind several other proteins in the bone morphogenetic protein (BMP) signaling pathway and act as a coupler between the membrane BMP receptor and the TAB1 TAK1 complex by binding to these proteins.
|Synthetic peptide corresponding to a portion of human ILP-2.|
|Antigen affinity chromatography|
|PBS with 0.02% sodium azide|
|RP1-315G1.5, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3, E3 ubiquitin-protein ligase XIAP, IAP-like protein, X-linked IAP, X-linked inhibitor of apoptosis protein, baculoviral IAP repeat-containing 4, baculoviral IAP repeat-containing protein 4, inhibitor of apoptosis protein 3|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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