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XRCC1, clone: 144, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA112640

Catalog No. 01-674-024


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Description

Description

XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.

A suggested positive control for this product is HT29, LS174T, HeLa cells or normal testis.
Specifications

Specifications

XRCC1
Monoclonal
0.2mg/mL
Assay Dependent
XRCC1
Liquid
XRCC1
Recombinant human XRCC1 protein.
Protein A
RUO
Antibody
Monoclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
144
Unconjugated
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
P18887
RCC
Murine
IgG2a
100μL
4° C
Primary
7515
Documents
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