XRCC1, clone: 144, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA112640
XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.A suggested positive control for this product is HT29, LS174T, HeLa cells or normal testis.
|Recombinant human XRCC1 protein.|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4|
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