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XRCC1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA525458

Catalog No. PIPA525458

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Specifications

Specifications

XRCC1
Polyclonal
PBS with 0.09% sodium azide
P18887
RCC, DNA repair protein XRCC1, X-ray repair cross-complementing protein 1, X-ray-repair, complementing defective, repair in Chinese hamster
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
7515
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Unconjugated
XRCC1
Liquid
XRCC1
KLH conjugated synthetic peptide between 407-435 amino acids from the central region of human XRCC1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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