X-ray repair complementing defective repair in Chinese hamster cells 3, Mouse, Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a full-length human XRCC3 protein.
Manufacturer: Abnova Corporation H00007517B01
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeqSequence: MDLDLLDLNPRIIAAIKKAKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLRTASLHLRGSSILTALQLHQQKERFPTQHQRLSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLMAQQPRLRTDVPGELLQKLRFGSQIFIEHVADVDTLLECVNKKVPVLLSRGMARLVVIDSVAAPFRCEFDSQASAPRARHLQSLGATLRELSSAFQSPVLCINQVTEAMEEQGAAHGPLGFWDERVSPALGITWANQLLVRLLADRLREEEAALGCPARTLRVLSAPHLPPSSCSYTISAEGVRGTPGTQSH
|X-ray repair complementing defective repair in Chinese hamster cells 3|
|XRCC3 (NP_005423.1, 1 a.a. ~ 346 a.a) full-length human protein.|
|Mouse polyclonal antibody raised against a full-length human XRCC3 protein.|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
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