ZAK Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527881
PA5-27881 targets ZAK in WB applications and shows reactivity with Human samples. The PA5-27881 immunogen is recombit fragment corresponding to a region within amino acids 306 and 609 of Human ZAK. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
|Recombit fragment corresponding to a region within amino acids 306 and 609 of Human ZAK|
|Antigen affinity chromatography|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|AZK, MLK7, MLT, MLTK, MRK, mlklak, pk, HCCS-4, MLK-like mitogen-activated protein triple kinase, human cervical cancer suppressor gene 4 protein, mitogen-activated protein kinase kinase kinase MLT, mixed lineage kinase 7, mixed lineage kinase with a leucine zipper and a sterile alpha motif, mixed li|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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