ZBED3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520767
Despite its predicted molecular weight, ZBED3 often migrates at a higher molecular weight in SDS-PAGE. A suggested positive control is A-20 cell lysate. PA5-20767 can be used with blocking peptide PEP-0881.Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression.
|A 17 amino acid peptide from near the amino terminus of human ZBED3.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|PBS with 0.02% sodium azide|
|2610005H11Rik; zinc finger BED domain-containing protein 3; zinc finger, BED domain containing 3|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|361881, 72114, 84327|
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