ZBTB2 Rabbit anti-Canine, Equine, Human, Marsupial, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523440
DescriptionZBTB2 is a member of the POK (POZ domain Krüppel-like zinc finger) family and plays an important role in cell cycle regulation. It is a transcription factor and a potent repressor of the ARF-HDM2-p53-p21 pathway. ZBTB2 represses the transcription of the p21, p53 and ARF genes and activates HDM2 gene. ZBTB2 and Sp1 compete with each other in binding to the GC-box 5/6 elements and the two p53 binding elements. ZBTB2 directly interacted with p53 via its zinc fingers, inhibiting p53 binding and repressing transcription activation by p53.
|Synthetic peptide (468 CQNQNSDVFALDEGRS 483) of ZBTB2 protein.|
|Canine, Equine, Human, Marsupial, Mouse, Non-human primate, Rat|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.05% BSA and 0.05% sodium azide|
|ZNF437, zinc finger and BTB domain-containing protein 2|
|-20° C, Avoid Freeze/Thaw Cycles|
|100060294, 308126, 381990, 484036, 57621|
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