ZC3HAV1 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520986
A suggested positive control is Hela cell lysate. PA5-20986 can be used with blocking peptide PEP-1100.The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses.
|A 14 amino acid peptide near the carboxy terminus of human ZC3HAV1.|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 0.02% sodium azide|
|PRO1677, FLB6421, PARP13, ZAP, ZC3H2, ZC3HDC2; zinc finger CCCH domain-containing protein 2; zinc finger CCCH-type antiviral protein 1|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
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