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ZC3HAV1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520986

Catalog No. PIPA520986


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Description

Description

A suggested positive control is Hela cell lysate. PA5-20986 can be used with blocking peptide PEP-1100.

The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses.
Specifications

Specifications

ZC3HAV1
Polyclonal
Unconjugated
ZC3HAV1
Liquid
ZC3HAV1
A 14 amino acid peptide near the carboxy terminus of human ZC3HAV1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q7Z2W4
PRO1677, FLB6421, PARP13, ZAP, ZC3H2, ZC3HDC2; zinc finger CCCH domain-containing protein 2; zinc finger CCCH-type antiviral protein 1
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
56829
Documents
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