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ZEB1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520979

Catalog No. PIPA520979


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Description

Description

A suggested positive control is Hela cell lysate. PA5-20979 can be used with blocking peptide PEP-1093.

ZEB1, initially identified as the delta-crystallin enhancer binding protein delta EF1, is a DNA-binding protein that binds to a modified E-box sequence and has been implicated in postgastrulation embryogenesis. ZEB1 binds to the promoter of several hemapoietic genes, including interleukin-2, CD4, GATA-3, and alpha(4)-integrin, and mice in which ZEB1 has been targeted show thymic atrophy, and severe defects in lymphocyte differentiation. Recent evidence suggests that ZEB1 also regulates the accumulation of adipose tissue and may play a role in obesity. Mutations in this gene have been associated with late-onset Fuchs endothelial corneal dystrophy.
Specifications

Specifications

ZEB1
Polyclonal
Unconjugated
ZEB1
Liquid
ZEB1
A 15 amino acid peptide near the center of human ZEB1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
P37275
RP11-472N13.4, AREB6, BZP, DELTAEF1, FECD6, NIL2A, PPCD3, TCF8, ZFHEP, ZFHX1A; delta-crystallin enhancer binding factor 1; negative regulator of IL2; posterior polymorphous corneal dystrophy 3; transcription factor 8 (represses interleukin 2 expression); zinc finger E-box-binding homeobox 1; zinc finger homeodomain enhancer-binding protein
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
6935
Documents
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