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ZIP10 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA521064

Catalog No. PIPA521064


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Description

Description

A suggested positive control is human spleen tissue lysate. PA5-21064 can be used with blocking peptide PEP-1178.

ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating that ZIP10 is positively regulated by thyroid hormones. ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and possibly a target for novel treatment strategies.
Specifications

Specifications

ZIP10
Polyclonal
Unconjugated
SLC39A10
Liquid
SLC39A10
An 18 amino acid peptide near the center of human ZIP10.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9ULF5, Q6P5F6
LZT-Hs2; ZIP-10; solute carrier family 39 (metal ion transporter), member 10; solute carrier family 39 member 10; zinc transporter ZIP10; zrt- and Irt-like protein 10
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
227059, 363229, 57181
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