SLC39A5 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA521070
A suggested positive control is human spleen tissue lysate. PA5-21070 can be used with blocking peptide PEP-1184.The zinc transporter ZIP5, also known as SLC39A5, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP5 is closely related to ZIP4, and is found in many of the same tissues, including intestine, pancreas, liver, and kidney, but unlike ZIP4, ZIP5 localizes to the basolateral membrane in kidney cells and its activity is not downregulated by zinc repletion. Recent evidence suggests that ZIP4 and ZIP5 are reciprocally regulated, with translation of ZIP5 mRNA decreasing and ZIP5 protein being rapidly internalized and degraded in response to zinc deficiency.
|A 17 amino acid peptide near the center of human ZIP5.|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|LZT-Hs7, ZIP5; ZIP-5; solute carrier family 39 member 5; zinc transporter ZIP5; zrt- and Irt-like protein 5|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
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