ZMYM1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA521089
A suggested positive control is rat lung tissue lysate. PA5-21089 can be used with blocking peptide PEP-1203.Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. As a member of the MYM (myeloproliferative and mental retardation) gene family, ZMYM1 is widely expressed in different tissues in eukaryotes under several forms derived by alternative splicing. While its function remains unknown, the related protein ZMYM2 has been shown to associate with and stabilize the LSD1-CoREST-HDAC1 (LCH) complex of chromatin through its MYM-type zinc fingers, thereby enhancing the transcriptional repression of several genes, suggesting that ZMYM1 may play a similar role.
|A 17 amino acid peptide near the carboxy terminus of human ZMYM1|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|RP11-248I9.4, MYM, RP11-181E22.4; zinc finger MYM-type protein 1; zinc finger, MYM domain containing 1|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|313604, 68310, 79830|
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