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ZNF346 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA521107

Catalog No. PIPA521107


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Description

Description

A suggested positive control is human kidney tissue lysate. PA5-21107 can be used with blocking peptide PEP-1221.

ZNF346, also known as JAZ (just another zinc-finger protein), is a nucleolar, zinc finger protein which preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids with high affinity via C2H2 zinc fingers. ZNF346 contains four C(2)H(2)-type zinc finger motifs that are connected by long (28-38) amino acid linker sequences. ZNF346 is expressed in all tissues tested and localizes to the nucleus, primarily the nucleolus. ZNF346 is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism. ZNF346 interacts with ILF3 in an RNA-independent manner and may be involved in cell growth and survival.
Specifications

Specifications

ZNF346
Polyclonal
Unconjugated
ZNF346
Liquid
Zfp346, ZNF346
A 20 amino acid peptide near the carboxy terminus of human ZNF346.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9UL40, Q9R0B7
JAZ, Zfp346; double-stranded RNA-binding zinc finger protein JAZ; just another zinc finger protein
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
23567, 26919
Documents
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