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ANXA7 (Annexin VII) Mouse anti-Human, Clone: OTI1C3, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA504925

Catalog No. 50-167-5512


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Description

Description

Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3 ft.-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.
Specifications

Specifications

ANXA7 (Annexin VII)
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P20073
ANX7, SNX, SYNEXIN
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
310
Western Blot
OTI1C3
Unconjugated
ANXA7
Liquid
ANXA7
Human recombit protein fragment corresponding to amino acids 105-411 of human ANXA7 produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
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