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AP 24534, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Potent multi-kinase and pan-Bcr-Abl inhibitor. Displays potent activity against cell lines expressing native Bcr-Abl or Bcr-AblT3151 (IC50 values are 0.37 and 2.0 nM respectively); also inhibits other Abl kinase domain mutants at nanomolar potencies. Exhibits inhibitory activity against PDGFRα, c-Src and c-Kit (IC50 values are 1.1, 5.4 and 12.5 nM respectively); potently inhibits FGFR and VEGFR family kinases. Orally active.
Specifications
Quantity | 50 mg |
Formula Weight | 532.56 |
Percent Purity | >98% |
Chemical Name or Material | AP 24534 |
Safety and Handling
Recommended Storage | Store at -20°C |
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