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APBA2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 197811AP

Catalog No. 50-173-2537


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Description

Description

APBA2, a member of the X11 protein family, is a phosphotyrosine-binding domain protein and is a neuronal adapter protein that interacts with amyloid precursor protein (APP) and neuritic plaques in the brains of patients with Alzheimer ft.s disease. It stabilizes APP and inhibits production of proteolytic APP fragments including the Abeta peptide that is deposited in the brains of Alzheimer ft.s disease patients. APBA2 is believed to be involved in signal transduction processes and is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Recent reports suggest that it may also be a candidate gene for autism.
Specifications

Specifications

APBA2
0.14 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P98084, Q99767
Adapter protein X11beta, APBA2, D15S1518E, HsT16821, LIN 10, Mint 2, MINT2, Neuron specific X11L protein, X11L
Rabbit
IgG
150 μL
-20°C
Primary
11784, 321
Western Blot
Unconjugated
APBA2
Liquid
Apba2
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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