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APC1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 217481AP

Catalog No. 50-173-3577


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Description

Description

Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC1, also known as mitotic checkpoint regulator (MCPR), is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex.
Specifications

Specifications

APC1
0.39 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P53995, Q9H1A4
ANAPC1, APC1, Mitotic checkpoint regulator, TSG24
Rabbit
IgG
150 μL
-20°C
Primary
17222, 311412, 64682
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
ANAPC1
Liquid
Anapc1
APC1 Fusion Protein Ag13399
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Documents
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