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Aphidicolin, White to off-white solid, Fisher BioReagents

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Quantity:
1mg
Packaging:
Poly Micro Tube
38966-21-1
C20H34O4
338.488
NOFOAYPPHIUXJR-APNQCZIXSA-N
aphidicolin, unii-192tj6pp19, ccris 1783, chembl29711, 3r,4r,4ar,6as,8r,9r,11as,11bs-4,9-bis hydroxymethyl-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta a naphthalene-3,9-diol, 9,15-cyclo-c,18-dinor-14,15-secoandrostane-4,17-dimethanol, 3,17-dihydroxy-4-methyl-, 3alpha,4alpha,5alpha,17alpha, +-aphidicolin, 8,11a-methano-11ah-cyclohepta a naphthalene-4,9-dimethanol, tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-, 3r-3-alpha,4-alpha,4a-alpha,6a-beta,8-beta,9-beta,11a-beta,11b-beta, +/--aphidicolin, aphidicolin, +/-
457964
CHEBI:2766
CC12CCC(C(C1CCC3C24CCC(C(C3)C4)(CO)O)(C)CO)O
38966-21-1
C20H34O4
338.488
NOFOAYPPHIUXJR-APNQCZIXSA-N
aphidicolin, unii-192tj6pp19, ccris 1783, chembl29711, 3r,4r,4ar,6as,8r,9r,11as,11bs-4,9-bis hydroxymethyl-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta a naphthalene-3,9-diol, 9,15-cyclo-c,18-dinor-14,15-secoandrostane-4,17-dimethanol, 3,17-dihydroxy-4-methyl-, 3alpha,4alpha,5alpha,17alpha, +-aphidicolin, 8,11a-methano-11ah-cyclohepta a naphthalene-4,9-dimethanol, tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-, 3r-3-alpha,4-alpha,4a-alpha,6a-beta,8-beta,9-beta,11a-beta,11b-beta, +/--aphidicolin, aphidicolin, +/-
457964
CHEBI:2766
CC12CCC(C(C1CCC3C24CCC(C(C3)C4)(CO)O)(C)CO)O

Isolated from Nigrospora orycae

  • Isolated from the fungus Nigrospora orycae and functions as reversible inhibitor of eukaryotic DNA replication
  • Specifically inhibits DNA polymerase α
  • Blocks cell cycle at early S phase
  • Poorly soluble in water, freely soluble in methanol and moderately soluble in DMSO
  • For research use only
Packaging Poly Micro Tube
Color White
Quantity 1mg
Identification Pass Test
Assay Percent Range ≥98 %
Merck Index 15, 714
Solubility Information Soluble (25mg/mL DMSO or Methanol)
Formula Weight 338.49
Physical Form Solid
Percent Purity ≥99%
Chemical Name or Material Aphidicolin
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Emergency Overview
The toxicological properties have not been fully investigated. May cause eye, skin, and respiratory tract irritation.
NFPA
Health:

Signal Word: CAUTION!

Recommended Storage : 4°C