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APOB Mouse anti-Human, Clone: GF1, Abnova™

Mouse monoclonal antibody raised against native human APOB.

Manufacturer:  Abnova Corporation MAB12864

Catalog No. 89-933-576


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Description

Description

This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq]

Specifications

Specifications

APOB
GF1
Mouse monoclonal antibody raised against native human APOB.
In PBS, pH 7.4 (0.05% sodium azide).
FLDB
Mouse
IgG2b
500 ug
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Monoclonal
Human
ELISA, Immunohistochemistry (PFA fixed)
Unconjugated
ELISA Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) The optimal working dilution should be determined by the end user.
Liquid
APOB
Native purified human APOB.
Purified
RUO
Primary
338
SDS
Documents
Product Certifications
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