APOBR Mouse anti-Human, Clone: OTI2E6, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF807047

Catalog No. 50-166-8098

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remt lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG- VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages.

Specifications

• Antigen: APOBR
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: APOBR
• Gene Alias: APOB100R, APOB48R
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55911
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI2E6
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q0VD83
• Gene Symbols: APOBR
• Immunogen: Human recombit protein fragment corresponding to amino acids 780-1088 of human APOBR produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1