BioVision Inc Apolipoprotein E4/Pan-ApoE (human) ELISA Kit: Rapid & convenient assay for quantitative measurement of human ApoE4 in serum, plasma, cell lysate & cell culture supernatant, & cerebrospinal fluid. Detection range: 50 ng to 800 ng/ml. 100 assays.
Manufacturer: BioVision Inc K4699100
Apolipoprotein E4/Pan-ApoE (human) ELISA Kit: ApoE transports lipoproteins, fat-soluble vitamins, and cholesterol via the lymph system to the blood. ApoE exists as three major isoforms, including ApoE2, ApoE3, and ApoE4. Recently, ApoE4 has been implicated in Alzheimer's disease (AD). ApoE4 is the first risk gene identified in Alzheimer's research, and remains the gene with strongest impact. Everyone inherits a copy of ApoE gene from each parent. Those who inherit one copy of ApoE4 have an increased risk of developing AD (about a quarter of the human population). Those who inherit two copies of ApoE4 have an even higher risk. In addition to raising risk, ApoE4 may tend to make AD symptoms appear at a younger age. BioVision's ApoE4 ELISA kit is a sandwich ELISA assay for the quantitative measurement of human ApoE4. The density of color is proportional to the amount of ApoE4 captured from the samples. Sensitivity of the kit is 25 ng/ml and detection range is from 50 ng to 800 ng/ml.
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