APP Monoclonal Antibody (OTI6B7), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA500992

Catalog No. 50-167-2134

Description

Amyloid Precursor Protein (APP) or Amyloid beta protein functions as a cell surface kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1; APP is rapidly internalized via clathrin-coated pits. APP is important for neurite growth, neuronal adhesion and axonogenesis. Mutations in the APP gene can lead to Alzheimer disease 1 (AD1). This anitbody recognizes APP (b-APP770) with a MW of approximately 100kDa.

Specifications

• Antigen: APP
• Classification: Monoclonal
• Concentration: 0.73 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P05067
• Gene Symbols: APP
• Immunogen: Full length human recombit protein of human APP produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI6B7
• Conjugate: Unconjugated
• Gene: APP
• Gene Alias: AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, preA4
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 351
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid