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Aquaporin 4 Mouse anti-Human, Clone: CL0178, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524587

Catalog No. PIMA524587


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Description

Description

Immunogen sequence: CPDVEFKRRF KEAFSKAAQQ TKGSYMEVED NRSQVETDDL ILKPGVVHVI DVDRGEEKKG KDQSGEVLSS V Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 92%. Binds to an epitope located within the peptide sequence FKRRFKEAFS as determined by overlapping synthetic peptides.

In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol.
Specifications

Specifications

Aquaporin 4
Monoclonal
0.5 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
P55087
Aquaporin 4, Aquaporin4, Aquaporin-4, AQP-4, Mercurial-insensitive water channel, MIWC, WCH4, AQP4
Mouse
IgG1
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
361
Immunohistochemistry, Western Blot
CL0178
Unconjugated
AQP4
Liquid
AQP4
Recombit protein corresponding to Human Aquaporin 4
Protein A
RUO
Antibody
Monoclonal
Human
Documents
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