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  8. AR-A 014418, Tocris Bioscience™

AR-A 014418, Tocris Bioscience™

Catalog Number 396610
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
487021-52-3
C12H12N4O4S
308.312
YAEMHJKFIIIULI-UHFFFAOYSA-N
gsk-3beta inhibitor viii, 1-4-methoxyphenyl methyl-3-5-nitro-1,3-thiazol-2-yl urea, unii-87ksh90q6d, 1-4-methoxybenzyl-3-5-nitrothiazol-2-yl urea, n-4-methoxybenzyl-n'-5-nitro-1,3-thiazol-2-yl urea, gsk-3, a inhibitor viii, n-4-methoxyphenyl methyl-n'-5-nitro-2-thiazolyl urea, insolution gsk-3beta inhibitor viii, n-4-methoxybenzyl-n′-5-nitro-1,3-thiazol-2-yl urea, gsk 3beta inhibitor viii
448014
CHEBI:46044
1-[(4-methoxyphenyl)methyl]-3-(5-nitro-1,3-thiazol-2-yl)urea
COC1=CC=C(C=C1)CNC(=O)NC2=NC=C(S2)[N+](=O)[O-]
This item is not returnable. View return policy
487021-52-3
C12H12N4O4S
308.312
YAEMHJKFIIIULI-UHFFFAOYSA-N
gsk-3beta inhibitor viii, 1-4-methoxyphenyl methyl-3-5-nitro-1,3-thiazol-2-yl urea, unii-87ksh90q6d, 1-4-methoxybenzyl-3-5-nitrothiazol-2-yl urea, n-4-methoxybenzyl-n'-5-nitro-1,3-thiazol-2-yl urea, gsk-3, a inhibitor viii, n-4-methoxyphenyl methyl-n'-5-nitro-2-thiazolyl urea, insolution gsk-3beta inhibitor viii, n-4-methoxybenzyl-n′-5-nitro-1,3-thiazol-2-yl urea, gsk 3beta inhibitor viii
448014
CHEBI:46044
1-[(4-methoxyphenyl)methyl]-3-(5-nitro-1,3-thiazol-2-yl)urea
COC1=CC=C(C=C1)CNC(=O)NC2=NC=C(S2)[N+](=O)[O-]

Description

Selective GSK-3 inhibitor

Selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC50 = 104 nM). Exhibits specificity for GSK-3 over cdk2 and cdk5 (IC50 values are > 100 μM) and over 26 other kinases. Inhibits β-amyloid-mediated neurodegeneration in hippocampal slices.
Quantity 10 mg
Formula Weight 308.31
Percent Purity >99%
Chemical Name or Material AR-A 014418

Safety and Handling

Recommended Storage Store at +4°C
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