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Arfaptin 1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549981

Catalog No. PA549981


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Description

Description

The antibody detects endogenous levels of total Arfaptin 1 protein.

Arfaptin 1 is an ARF binding protein that inhibits PLD activation, vesicular trafficking and secretion. In the present report, we show that arfaptin 1 interacts with  ft.high speed ft. membranes independently of ARF. However, addition of myristoylated ARF3 (myrARF3) increases the association of arfaptin 1 with the membranes, suggesting that arfaptin 1 and ARF form a complex on the Golgi. Utilizing several deletion mutants of arfaptin 1 it is shown that the association of arfaptin 1 with myrARF3 is mediated via two binding sites on arfaptin 1. These two domains are needed for arfaptin 1 inhibition of PLD activation by myrARF3 in vitro.
Specifications

Specifications

Arfaptin 1
Polyclonal
Unconjugated
ARFIP1
Liquid
ARFIP1
Synthesized peptide derived from internal of human ARFIP1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P53367, Q9JHU5
ADP-ribosylation factor interacting 1, arfaptin-1, ARFP1,
Rabbit
IgG
100 μL
-20°C
Primary
27236, 60382, 99889
Documents
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