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ARFGAP1 Mouse anti-Human, Non-human primate, Clone: OTI1F6, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525466

Catalog No. PIMA525466


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Description

Description

ArfGAP1 is a 406 amino acid containing regulatory protein with an Arf-GAP domain known to be involved in the activation of the GTPase activity of ADP ribosylation factor (ARF). ArfGAP1, a GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1), promotes the hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles thus playing an important role in membrane trafficking and/or vesicle transport. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been reported. Ubiquitous expression of ArfGAP1 is seen in most tissues.
Specifications

Specifications

ARFGAP1
Monoclonal
0.63 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q8N6T3
RP11-261N11.1, ARF1GAP, HRIHFB2281, ADP-ribosylation factor 1 GTPase activating protein, ADP-ribosylation factor 1 GTPase-activating protein, ADP-ribosylation factor GTPase-activating protein 1, ARF GAP 1, ARF1 GAP, ARF1-directed GTPase-activating protein, GAP protein
Mouse
IgG2b
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
55738, 719734
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI1F6
Unconjugated
ARFGAP1
Liquid
ARFGAP1
Full length human recombit protein of ARFGAP1 produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human, Non-human primate
Documents
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