Argonaute 1 Mouse anti-Human, Clone: OTI4G1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527411
DescriptionSmall interfering RNAs (siRNAs) have gained much attention for their powerful ability to suppress gene expression. Introduction of double-stranded RNA (dsRNA), that are homologues in sequence to a gene, has proven to suppress that gene ft.s expression through a process known as RNA interference (RNAi); this process post-transcriptionally silences a gene through mRNA inhibition or degradation. Both biochemical and genetic studies have led to the identification of two, conserved gene families that are universal components of the interference process. These are the Dicer family, which is comprised of members of the Ribonuclease III family of enzymes, and the Argonaute gene family. Argonaute proteins addition to their role in RNAi process, may also influence development, such as, stem cell fate determination.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|EIF2C1; eukaryotic translation initiation factor 2C, 1; AGO1; EIF2C; GERP95; Q99 ; Golgi Endoplasmic Reticulum protein 95 kDa; argonaute 1; putative RNA-binding protein Q99|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 226-490 of EIF2C1 produced in E.coli|
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