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ARHGAP18 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549609

Catalog No. PA549609

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

ARHGAP18 is one member of the human RhoGAP family with approximately 80 RhoGAP proteins known to be encoded in the human genome. Rho proteins belong to the Ras superfamily that is composed of over 50 members divided into six families, including Ras, Sar, Rho, Ran, Rab and Arf. Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. ARHGAP18 is linked to Ras, and thus, to EGFR-mediated proliferation, migration and differentiation. ARHGAP18 is precisely contained within chromosome 6q22-24, which has been shown to be linked to schizophrenia, suggesting that ARHGEP18 may play a role in this condition.
Specifications

Specifications

ARHGAP18
Polyclonal
PBS with 0.09% sodium azide
Q8N392
Rho GTPase-activating protein 18, MacGAP, Rho-type GTPase-activating protein 18, ARHGAP18 (HGNC:21035)
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
93663
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
ARHGAP18
Liquid
ARHGAP18
KLH conjugated synthetic peptide between 180-207 amino acids from the Central region of human ARHGAP18.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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