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ARHGAP24 Rabbit anti-Canine, Human, Mouse, Rat, Zebrafish, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 188341AP

Catalog No. 50-173-2250


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Description

Description

The antibody may recognize all the isoforms of ARHGAP24 except isoform 5.

Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.
Specifications

Specifications

ARHGAP24
0.31 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q5U2Z7, Q8C4V1, Q8N264
ARHGAP24, Filamin A associated RhoGAP, FILGAP, p73, p73RhoGAP, RC GAP72, RCGAP72, Rho type GTPase activating protein 24, RhoGAP of 73 kDa, Sarcoma antigen NY SAR 88
Rabbit
IgG
150 μL
-20°C
Primary
100005116, 231532, 305156, 478463, 83478
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
ARHGAP24
Liquid
ARHGAP24
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Canine, Human, Mouse, Rat, Zebrafish
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