Tocris™ AS 1949490

SH2 domain-containing inositol 5'-phosphatase 2 (SHIP2) inhibitor

Manufacturer: Tocris™ 3718/50

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Catalog No. 37-185-0R

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Disclaimers:

For Research Use Only


    Specifications

    Product Type AS 1949490
    Inhibitors AS 1949490
    Purity >99
    Molecular Weight 371.88
    Quantity 50mg

    Selective SHIP2 (SH2 domain-containing inositol 5'-phosphatase 2) inhibitor (IC50 values are 0.34µM and 0.62µM for mouse and human respectively); displays approximately 30-fold affinity for SHIP2 over SHIP1. Increases insulin-induced phosphorylation of Akt in L6 myotubules. Stimulates activation of glucose metabolism; regulates gluconeogenesis in vitro and in vivo and exhibits antidiabetic effects.

    • Chemical Name: 3-[(4-Chlorophenyl)methoxy]-N-[(1S)-1-phenylethyl]thiophene-2-carboxamide
    • Formula: C20H18ClNO2S
    • CAS Number: 1203680-76-5
    • Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
    • Purity: >99

  • Description & Specifications

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