Tocris AS 2034178
Selective FFA1 (GPR40) agonist
Manufacturer: Tocris 5035/50
DescriptionSelective free fatty acid receptor 1 (FFA1/GPR40) agonist. Exhibits selectivity for GPR40 over GPR41, GPR43, GPR119, GPR120 and PPARγ. Induces glucose-dependent insulin secretion in pancreatic MIN6 cells and in vivo. Enhances insulin sensitivity in a type 2 diabetes model in vivo. Orally available.
- Chemical Name: 2-Fluoro-4-[[[1,2,3,4-Tetrahydro-1-(2-phenoxyethyl)-5-quinolinyl]methyl]amino]benzenepropanoic acid
- Formula: C27H29FN2O3
- CAS Number: 1030846-42-4
- Solubility: Soluble to 50mM in DMSO and to 20mM in ethanol
- Purity: >98
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