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Tocris Bioscience™ AS 2444697 Available on GSA/VA Contract for Federal Government customers only.

Potent and selective IRAK4 inhibitor

$259.00 - $1088.00

Specifications

Chemical Name or Material N-[3-Aminocarbonyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]-2-(2-methyl-4-pyridinyl)-4-oxazolecarboxamide hydrochloride
Molecular Formula C19H20N6O4.HCl
CAS 1287665-60-4
Product Type Target: Other Kinase Inhibitors
Formula Weight 432.86
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
543010 Available on GSA/VA Contract for Federal Government customers only. View Documents Tocris Bioscience™
5430/10
10mg Each for $259.00
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543050 Available on GSA/VA Contract for Federal Government customers only. View Documents Tocris Bioscience™
5430/50
Each for $1,088.00
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Description

Description

Potent and selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor (IC50 = 21 nM). Displays 30-fold selectivity for IRAK4 over IRAK1. Inhibits LPS-induced TNF-α and IL-6 production in PBMCs in vitro. Renoprotective and anti-inflammatory in a rodent model of chronic kidney disease.

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Specifications

Specifications

N-[3-Aminocarbonyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]-2-(2-methyl-4-pyridinyl)-4-oxazolecarboxamide hydrochloride
1287665-60-4
432.86
C19H20N6O4.HCl
Target: Other Kinase Inhibitors
Safety and Handling

Safety and Handling

Recommended Storage : Desiccate at RT

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