ASCC1 Monoclonal Antibody (OTI1H10), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA503788

Catalog No. 50-167-4593

Description

This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

Specifications

• Antigen: ASCC1
• Classification: Monoclonal
• Concentration: 0.34 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q8N9N2
• Gene Symbols: ASCC1
• Immunogen: Full length human recombit protein of human ASCC1 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Western Blot
• Clone: OTI1H10
• Conjugate: Unconjugated
• Gene: ASCC1
• Gene Alias: ASC1p50, CGI-18, SMABF2, p50
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51008
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid