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ASCC1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550355

Catalog No. PA550355


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Description

Description

The antibody detects endogenous levels of total ASCC1 protein.

This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
Specifications

Specifications

ASCC1
Polyclonal
Unconjugated
ASCC1
Liquid
ASCC1
Fusion protein corresponding to residues near the C terminal of human activating signal cointegrator 1 complex subunit 1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
1.2 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q8N9N2
p50, CGI-18, ASC1p50
Rabbit
IgG
100 μL
-20°C
Primary
51008
Documents
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