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ASH2L Rabbit anti-Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA540070

Catalog No. PA540070


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Description

Description

Ash2 is a component of the Set1/Ash2 histone methyltransferase (HMT) complex. This complex specifically methylates K4 of histone H3, thereby activating transcription. Methylation of K4 is blocked by premethylation of the neighboring K9, a repressor of transcription. This indicates that the Set1/Ash2 HMT complex mediates the crosstalk between K9 methylation and K4 methylation. Ash2 plays a role in hematopoiesis and may be associated with some kinds of leukemia.
Specifications

Specifications

ASH2L
Polyclonal
whole serum with 0.05% sodium azide
Q91X20
ASH2, ASH2L1, ASH2L2, Bre2, ASH2-like protein, set1/Ash2 histone methyltransferase complex subunit ASH2
Rabbit
IgG
RUO
Antibody
Polyclonal
Mouse
ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
Ash2l
Liquid
ASH2L
Three different KLH-conjugated synthetic peptides, 2 containing an amino acid sequence from the central and 1 containing an amino acid sequence from the C-terminal part of the protein corresponding to mouse Ash2 (absent, small, or homeotic 2).
100 μL
-20°C or -80°C if preferred
Primary
23808
Documents
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