Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

ASIC1 Mouse anti-Mouse, Rat, Clone: S271-44, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527640

Catalog No. PIMA527640

Add to cart



This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is expressed in most if not all brain neurons, and it may be an ion channel subunit; however, its function as an ion channel remains unknown. Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. ASIC1 is permeable for Ca(2+), Li(+) and K(+) and is expressed in dorsal root ganglia, sciatic nerves, olfactory bulb, neo and allocortical regions, dentate granule cells, pyramidal cells of CA1-CA3 subfields of the hippocampal formation, habenula, basolateral amygdaloid nuclei, and in the Purkinje and granule cells of the cerebellum. It is diffusely detected over most other regions of the basal ganglia, including thalamic nuclei, substantia nigra, striatum and globus pallidus, hypothalamus, midbrain, pons, medulla and choroid plexus. Isoform 3 is expressed only in dorsal root ganglion while isoform 1 is expressed in DRG, spinal chord, trigeminal ganglia and the trigeminal mesencephalic nucleus.


1 mg/ml
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
P55926, Q6NXK8
ACCN2, Acid-sensing (proton-gated) ion channel, Acid-sensing ion channel 1, Amiloride-sensitive cation channel 2 neuronal, BNAC2, Brain sodium channel 2
100 μg
11419, 79123
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Fusion protein amino acids 460-526 (Cytoplasmic C-terminus) of mouse ASIC1
Protein G
Mouse, Rat
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit