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Tocris Bioscience™ AT 101 Inhibitor
Low molecular weight, organic compound that may help regulate biological process.
Specifications
| Description | CAS: 90141-22-3 |
|---|---|
| Formulation | C30H30O8 |
| For Use With (Application) | Inhibits apoptosis |
| Molecular Weight (g/mol) | 518.56g/mol |
| Solubility | Soluble to 100mM in DMSO, 100mM in ethanol |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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NB336710MG
|
Tocris Bioscience™
NB336710MG |
10 mg | Item Discontinued This item has been discontinued by the supplier. Please Sign In to view product availability in your area. | N/A | |||||
|
NB336750MG
|
Tocris Bioscience™
NB336750MG |
50 mg | Item Discontinued This item has been discontinued by the supplier. Please Sign In to view product availability in your area. | N/A | |||||
Description
Biological Activity:
R-(-)-enantiomer of gossypol. Mimics BH3 domains of Bcl-2, Bcl-XL and Mcl-1. Disrupts heterodimerization of Bcl-2 with proapoptotic family members. Induces apoptosis in vitro through activation of caspase-9; cytotoxic to multiple myeloma and drug-resistant cell lines. Delays onset of androgen-independent growth of VCaP prostate cancer xenografts in vivo.
Storage: Store the unopened product at 2° to 8°C. Do not use past expiration date.
Specifications
| CAS: 90141-22-3 | |
| Inhibits apoptosis | |
| Soluble to 100mM in DMSO, 100mM in ethanol | |
| AT 101 |
| C30H30O8 | |
| 518.56g/mol | |
| -20°C | |
| Dark Purple |
For Laboratory Research Use Only
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