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ATF1 Rabbit anti-Human, Unconjugated, Polyclonal, Active Motif™ Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

$135.30 - $534.00

Specifications

Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Antigen ATF1
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-3501 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
61564
10 μL
Each for $135.30
Add to cart
 
50-199-3500 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
61563
100 μL
Each for $534.00
Add to cart
 
Description

Description

This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.
Specifications

Specifications

Polyclonal
Primary
ATF1
Unconjugated
SDS
Product Certifications
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